Python jobs in San Francisco

445 open jobs, 31 posted in the last 7 days and 128 remote. Updated 12 October 2026. Every job links to the employer's own page.

Hiring most: OpenAI (138), DoorDash USA (45), Databricks (41), Pinterest (32), Block (22). Skills named most often: Python (100%), Machine learning (38%), SQL (38%), REST APIs (36%), Stakeholder management (33%), System design (26%). Most roles are mid level.

Newest openings

• Machine Learning Engineer, Trust & SafetyVercel · Hybrid - San Francisco, New York City · posted 9 Oct 2026
• Software Engineer, API AgentsOpenAI · San Francisco · posted 9 Oct 2026
• Product Design New Grad (2027 Start)Databricks · San Francisco, California; Seattle, Washington · posted 9 Oct 2026
• Incident and Escalations Manager 3 - US-WestDatadog · Denver, Colorado, USA; San Francisco, California, USA · posted 9 Oct 2026
• IT Engineer Intern (Early Careers Summer 2027)Affirm · San Francisco, California, United States · posted 9 Oct 2026
• Credit Risk, Fraud StrategistStripe · South San Francisco · posted 9 Oct 2026
• Sr. Automation Engineer - IT Asset ManagementDatabricks · Bellevue, Washington; Mountain View, California; San Francisco, California; Seattle, Washi · posted 9 Oct 2026
• Global Demo EngineerNotion · San Francisco, California · posted 9 Oct 2026
• Software Engineer, Machine Learning Platform - Gen AIDoorDash USA · San Francisco, CA; Sunnyvale, CA; Seattle, WA · posted 8 Oct 2026
• Software Engineer, Machine Learning Platform - MDXDoorDash USA · San Francisco, CA; Sunnyvale, CA; • Seattle, WA · posted 8 Oct 2026
• Software Engineer, ML Serving PlatformDoorDash USA · San Francisco, CA; Sunnyvale, CA; • Seattle, WA · posted 8 Oct 2026
• Data Scientist, FinEngOpenAI · San Francisco · posted 8 Oct 2026
• Senior Data Engineer, ProductBlock · Bay Area, CA, United States of America · posted 8 Oct 2026
• Hardware Engineer (Electrical)Navi · San Francisco · posted 8 Oct 2026
• Sr. Solutions ArchitectDatabricks · San Francisco, California; Seattle, Washington · posted 8 Oct 2026
• Product Solutions Architect - FinOpsDatadog · Boston, Massachusetts, USA; Denver, Colorado, USA; New York, New York, USA; San Francisco, · posted 8 Oct 2026
• Solutions Engineer Intern 2027 (USA)Pinterest · San Francisco, CA, US; Remote, US · posted 8 Oct 2026
• Software Engineer, Intern - Labs (Summer 2027)DoorDash USA · San Francisco, CA; Sunnyvale, CA · posted 8 Oct 2026
• IT Systems EngineerVercel · Hybrid - San Francisco, New York City, Austin · posted 7 Oct 2026
• Tech Lead Manager, PlatformChime Financial, Inc · San Francisco, CA, USA · posted 7 Oct 2026
• Desktop Support TechnicianNew Relic · San Francisco, California, USA · posted 7 Oct 2026
• PhD Machine Learning Software Engineer Intern (Summer 2027)Lyft · San Francisco, CA · posted 6 Oct 2026
• Senior Data Scientist, Finance & StrategyChime Financial, Inc · San Francisco, CA, USA · posted 6 Oct 2026
• Staff Data Scientist, Trust and SafetyPinterest · San Francisco, CA, US; Remote, US · posted 6 Oct 2026
• Technical Support EngineerPlaid · San Francisco HQ · posted 6 Oct 2026
• Business Systems Analyst, IT Vendor OperationsBlock · Bay Area, CA, United States of America · posted 6 Oct 2026
• Product Acceleration SpecialistOkta · San Francisco, California · posted 6 Oct 2026
• Security Software Engineer II, Detection and ResponsePinterest · San Francisco, CA, US; Remote, US · posted 5 Oct 2026
• PhD Intern, AI Applied Scientist (2027)Figma · San Francisco, CA • New York, NY · posted 5 Oct 2026
• Manager II, Engineering, Ads Serving InfrastructurePinterest · Palo Alto, CA, US; San Francisco, CA, US · posted 5 Oct 2026
• Sr. Integrations Engineer, Supply Chain TechnologyOpenAI · San Francisco · posted 5 Oct 2026
• Software Engineer, Enterprise ControlsOpenAI · San Francisco · posted 3 Oct 2026
• Senior Security Engineer, Detection & ResponseBlock · Bay Area, CA, United States of America · posted 2 Oct 2026
• Senior Application Security EngineerChime Financial, Inc · San Francisco, CA, USA · posted 2 Oct 2026
• Software Engineer (Machine Learning) Intern (Summer 2027)Affirm · San Francisco, California, United States · posted 2 Oct 2026
• Tech Lead Manager, Machine Learning, Growth and MarketingChime Financial, Inc · San Francisco, CA, USA · posted 2 Oct 2026
• Senior Machine Learning Engineer - New Verticals Agentic FoundationsDoorDash USA · San Francisco, CA; Sunnyvale, CA; Seattle, WA; NewYork, NY · posted 2 Oct 2026
• Senior Software Engineer, Data PlatformChime Financial, Inc · San Francisco, CA, USA · posted 2 Oct 2026
• Security Engineer, Business Continuity & RiskBlock · Bay Area, CA, United States of America · posted 1 Oct 2026
• Staff Security Engineer, DoorDash Labs - AirDoorDash USA · San Francisco, CA · posted 1 Oct 2026
• Data Scientist II, Applied MLBrex · San Francisco, California, United States · posted 1 Oct 2026
• Master's Machine Learning Internship 2027 (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US; New York, NY, US · posted 1 Oct 2026
• Master's University Grad Machine Learning Engineer 2027 (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US; New York, NY, US · posted 1 Oct 2026
• PhD Machine Learning Internship 2027 (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US; New York, NY, US · posted 1 Oct 2026
• PhD University Grad Machine Learning Engineer (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US · posted 1 Oct 2026
• Data Scientist, Algorithms - Dynamic PricingLyft · San Francisco, CA · posted 1 Oct 2026
• Master's Data Science Internship 2027 (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US; New York, NY, US · posted 1 Oct 2026
• Master's University Grad Data Scientist (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US; New York, NY, US · posted 1 Oct 2026
• PhD Data Science Internship 2027 (USA)Pinterest · San Francisco, CA, US; Palo Alto, CA, US; Seattle, WA, US; New York, NY, US · posted 1 Oct 2026
• PhD Data Scientist, InternStripe · New York, Seattle, South San Francisco HQ · posted 1 Oct 2026
• Software Engineer, DevOpsOpenAI · San Francisco · posted 1 Oct 2026
• Full Stack Software Engineer, Sales PlatformOpenAI · San Francisco · posted 1 Oct 2026
• Developer AdvocateAsana · San Francisco · posted 1 Oct 2026
• Tech Lead Manager, Data Integration PlatformChime Financial, Inc · San Francisco, CA, USA · posted 1 Oct 2026
• Software Engineer Intern 2027 (USA)Pinterest · San Francisco, CA, US; Remote, US · posted 1 Oct 2026
• University Grad Software Engineer 2027 (USA)Pinterest · San Francisco, CA, US; Remote, US · posted 1 Oct 2026
• Sr. Staff Software Engineer, Product ML InfrastructurePinterest · Palo Alto, CA, US; San Francisco, CA, US · posted 30 Sep 2026
• Data Scientist, B2B Strategy & IntelligenceOpenAI · San Francisco · posted 30 Sep 2026
• Business Intelligence AnalystBlock · San Francisco, CA, United States of America · posted 29 Sep 2026
• Senior Insurance Data LeadDoorDash USA · San Francisco, CA · posted 29 Sep 2026

Showing the newest 60 of 445. See them all, ranked for you.

More Python jobs

Skills often asked for with it

Questions

How many Python jobs in San Francisco are open right now?

445 on 12 October 2026, of which 31 were posted in the last 7 days and 128 are remote.

Which employers are hiring for Python jobs in San Francisco?

The most openings are at OpenAI (138), DoorDash USA (45), Databricks (41), Pinterest (32), Block (22).

Which skills do Python jobs in San Francisco ask for most?

Counted from 445 postings with a description: Python (100%), Machine learning (38%), SQL (38%), REST APIs (36%), Stakeholder management (33%), System design (26%).

How do I find the Python jobs in San Francisco that fit me?

Set your level, location and skills on SkillFit Jobs and each job gets a match score out of 100 with the reasons. It is free and needs no sign-up.